I have a Pi4, with fresh install. Direwolf is configured and works a digi and igate.
I originally used a simple USB audio device and attempted to use VOX, with the expected poor performance.
I purchased a digirig mini and the Pi saw it once. Then direwolf could no longer see the mini and terminated.
I have read the PTT help and see that RF may have been the problem while testing on the bench and have made corrections, but now the Pi will not start the mini. I have restarted and tried all USB ports on the PI.
Is your Digirig Lite still recognized by the PC? If it is, then it is not damaged.
There were some reports of Raspberry PI computers, specifically Pi Zero not recognizing Digirig Lite’s sound card when connected directly. Having a hub or other device to condition the USB lines resolved the issue. Digirig Mobile and DR-891 have hubs internally and don’t experience this issue.